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RNA FOLDING

Tracking RNA structures as RNAs transit through the cell

RNAs perform diverse cellular functions that are mediated at least in part by their structure. However, how RNA structure changes throughout the RNA lifecycle and how these changes affect RNA function remain incompletely understood. A detailed in vivo characterization of RNA structure in various cellular subcompartments now provides insights into how RNA structural changes influence translation, RNA decay, protein binding and RNA modification.

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The authors declare no competing interests.

Correspondence to Julius B. Lucks.

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Fig. 1: RNA structures throughout cellular subcompartments.