Poster | Published:

Epitranscriptome regulation

Nature Structural & Molecular Biology (2018) | Download Citation

Dynamic modifications of RNAs play essential regulatory roles during RNA-processing events and thereby affect gene expression as well as cellular functions, development and diseases such as cancer. Dan Dominissini and Gideon Rechavi illustrate the broad relevance of ‘epitranscriptome regulation’, as this phenomenon is now known, using as an example the functions and mechanisms of action of N 6-methyladenosine (m6A), an abundant and well-studied RNA modification.

This poster is freely available online thanks to support from Accent Therapeutics, Inc.

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Affiliations

  1. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

    • Dan Dominissini
    •  & Gideon Rechavi
  2. Cancer Research Center and Wohl Institute for Translational Medicine, Chaim Sheba Medical Center, Tel-Hashomer, Israel

    • Dan Dominissini
    •  & Gideon Rechavi

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Correspondence to Dan Dominissini or Gideon Rechavi.

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DOI

https://doi.org/10.1038/s41594-018-0140-7