RNA MODIFICATIONS

U-tail as a guardian against invading RNAs

RNA uridylation offers a basis for diverse post-transcriptional regulation. Two recent studies reveal new roles of uridylation in immune defense against viruses and retrotransposons.

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Fig. 1: Uridylation has diverse roles in RNA metabolism.
Fig. 2: Terminal uridyltransferases restrict viruses and retrotransposons.

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Correspondence to V. Narry Kim.

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Yeo, J., Kim, V.N. U-tail as a guardian against invading RNAs. Nat Struct Mol Biol 25, 903–905 (2018). https://doi.org/10.1038/s41594-018-0139-0

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