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Nanobody generation

Speed up to find the right ones: rapid discovery of functional nanobodies

Nanobodies have emerged as highly versatile and useful binding molecules in biomedical research. A technical report describes a cost- and time-effective in vitro platform that facilitates the generation of desired nanobodies, including conformationally selective nanobodies against agonist-bound G-protein-coupled receptors (GPCRs).

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Correspondence to Ulrich Rothbauer.

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Further reading

Fig. 1: Schematic comparison of methods to generate nanobodies.