An efficient tool for neurite tracing has been developed that reconstructed the complete axons of 6,357 individual projection neurons in the mouse prefrontal cortex (PFC). The resulting single-neuron projectome analysis revealed comprehensive PFC neuron subtypes, topographic organization of PFC axon projections, modular structure within the PFC and correspondence with single-cell transcriptomes.
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References
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This is a summary of: Gao, L. et al. Single-neuron projectome of mouse prefrontal cortex. Nat. Neurosci. https://doi.org/10.1038/s41593-022-01041-5 (2022)
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Organizing principles of the prefrontal cortex from a single-neuron projectome. Nat Neurosci 25, 408–409 (2022). https://doi.org/10.1038/s41593-022-01038-0
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DOI: https://doi.org/10.1038/s41593-022-01038-0
