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PAIN CIRCUITRY

Anesthesia analgesia in the amygdala

Nature Neuroscience volume 23, pages 783–785 (2020)Cite this article

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General anesthetics during surgery are presumed to block pain by dampening brain activity and promoting loss-of-consciousness. A new study shows that anesthetics activate an endogenous analgesia neural ensemble in the central nucleus of the amygdala.

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Fig. 1: Anesthesia co-opts amygdalar analgesia ensembles.

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  1. These authors contributed equally.

Authors and Affiliations

  1. Department of Psychiatry and Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Nora M. McCall, Jessica A. Wojick & Gregory Corder

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  1. Nora M. McCall
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  2. Jessica A. Wojick
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  3. Gregory Corder
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Correspondence to Gregory Corder.

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McCall, N.M., Wojick, J.A. & Corder, G. Anesthesia analgesia in the amygdala. Nat Neurosci 23, 783–785 (2020). https://doi.org/10.1038/s41593-020-0645-3

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