Extended Data Fig. 5: Structured inhibition is necessary for repulsive serial biases at far distances. | Nature Neuroscience

Extended Data Fig. 5: Structured inhibition is necessary for repulsive serial biases at far distances.

From: Interplay between persistent activity and activity-silent dynamics in the prefrontal cortex underlies serial biases in working memory

Extended Data Fig. 5

Top panel, illustration of two different models that have different inhibitory connectivity profiles. On the left, inhibitory connectivity strength from inhibitory to excitatory neurons is similar for all distances between their preferred locations. On the right, inhibition is structured such that similarly tuned neurons have stronger feedback inhibition. This shows that repulsive biases are caused by repulsive interactions between simultaneously active bumps in the network39,40, and are absent when there is no reignited bump that recruits localized inhibition at the flanks of the pre-cue bump of activity.

Back to article page