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ENTERIC NERVOUS SYSTEM

Revealing the complexity of the gut’s brain

A new study proposes an exciting new model of neuronal diversification in the developing enteric nervous system (ENS) and establishes a detailed molecular taxonomy for enteric neurons. Their findings open new horizons for ENS research and for developing cell-based therapies for ENS disorders.

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Fig. 1: Twelve unique ENCs arise from a binary fate split during development with subsequent diversification of postmitotic neuronal populations.

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Correspondence to Julia Ganz.

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Ganz, J. Revealing the complexity of the gut’s brain. Nat Neurosci 24, 1–2 (2021). https://doi.org/10.1038/s41593-020-00769-2

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