PNS REGENERATION

Schwann cell energy to die for

A new study shows that, immediately after axon injury, glycolysis is increased in Schwann cells to provide axons with energy and prevent them from degenerating. The authors also identify possible therapeutic targets that could be modulated to promote axonal protection.

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Fig. 1: Schwann cells’ glycolytic switch in Wallerian degeneration.

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Correspondence to Amelia Trimarco or Carla Taveggia.

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Trimarco, A., Taveggia, C. Schwann cell energy to die for. Nat Neurosci 23, 1179–1181 (2020). https://doi.org/10.1038/s41593-020-00707-2

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