Supplementary Figure 7: Morphological similarity of OPC perivascular clusters in MS and Olig2cre:APCfl/fl. | Nature Neuroscience

Supplementary Figure 7: Morphological similarity of OPC perivascular clusters in MS and Olig2cre:APCfl/fl.

From: Aberrant oligodendroglial–vascular interactions disrupt the blood–brain barrier, triggering CNS inflammation

Supplementary Figure 7

Side by side example comparisons of morphological similarity of OPC perivascular clusters (vasculature marked with CD31, green) marked by OLIG2+ (red) in MS active lesions (a) and with TdTomato (red) in postnatal brain of Olig2cre:APCfl/fl:TdTomato (b). Arrows in each panel indicate OPC clusters. Scale bars, 20 μm in all panels. For all staining results, experiments were repeated at least three times independently with similar results.

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