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NEURAL CIRCUITS

The two faces of PVN CRF neurons

In this issue of Nature Neuroscience, Kim and colleagues report that corticotropin-releasing factor neurons in the paraventricular nucleus, known essential regulators of the neuroendocrine axis, encode the valence of environmental stimuli through a bidirectional strategy and modulate animals’ immediate behavioral responses.

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Fig. 1: PVN CRF neurons biphasically encode the valence of encountered stimuli and bidirectionally modulate animals’ behavioral responses.

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Correspondence to Minmin Luo.

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Lin, R., Yan, T. & Luo, M. The two faces of PVN CRF neurons. Nat Neurosci 22, 508–510 (2019). https://doi.org/10.1038/s41593-019-0363-x

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