COMPUTATIONAL PSYCHIATRY

Post-traumatic stress disorder as a disorder of prediction

Disproportionate reactions to unexpected stimuli and greater attention to perceived threat are cardinal symptoms of post-traumatic stress disorder. Computational psychiatry helps explain how these responses develop and result from abnormalities in learning and prediction during and after traumatic events.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Fig. 1: A computational psychiatry approach to investigating possible learning anomalies in PTSD.

References

  1. 1.

    Mahan, A. L. & Ressler, K. J. Trends Neurosci. 35, 24–35 (2012).

  2. 2.

    Homan, P. et al. Nat. Neurosci. https://dx.doi.org/s41593-018-0315-x (2019).

  3. 3.

    Brown, V. M. et al. eLife 7, e30150 (2018).

  4. 4.

    Huys, Q. J., Maia, T. V. & Frank, M. J. Nat. Neurosci. 19, 404–413 (2016).

  5. 5.

    Lissek, S. & van Meurs, B. Int. J. Psychophysiol. 98, 594–605 (2015).

  6. 6.

    Li, J., Schiller, D., Schoenbaum, G., Phelps, E. A. & Daw, N. D. Nat. Neurosci. 14, 1250–1252 (2011).

  7. 7.

    Ruderman, L. et al. Depress. Anxiety 33, 606–613 (2016).

  8. 8.

    Myers, C. E. PLoS One https://doi.org/10.1371/journal.pone.0072508 (2013).

  9. 9.

    Raymond, J. G., Steele, J. D. & Seriès, P. Front. Psychiatry 8, 1 (2017).

  10. 10.

    Browning, M., Behrens, T. E., Jocham, G., O’Reilly, J. X. & Bishop, S. J. Nat. Neurosci. 18, 590–596 (2015).

  11. 11.

    Watkins, L. E., Sprang, K. R. & Rothbaum, B. O. Front. Behav. Neurosci. 12, 258 (2018).

  12. 12.

    Green, B. Adv. Psychiatr. Treat. 19, 181–190 (2013).

  13. 13.

    Moutoussis, M., Shahar, N., Hauser, T. U. & Dolan, R. J. Compr. Psychiatry 2, 50–73 (2018).

Download references

Author information

Correspondence to Peggy Seriès.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark