Supplementary Figure 7: Integrate-and-fire motor neuron model. | Nature Neuroscience

Supplementary Figure 7: Integrate-and-fire motor neuron model.

From: Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Supplementary Figure 7

Schematic of the integrate and fire model and of the different synapses contacting this cell. b, Simulated inhibitory and excitatory post synaptic potentials (IPSPs/EPSPs) induced by the activation of a single Ia-inhibitory interneuron or a single group-Ia afferent fiber, respectively. c, Excitation threshold of our multicompartmental alpha motoneuron model. d, Number and amplitude of experimental and modeled EPSP/IPSPs induced from the synaptic contacts originating from group-Ia afferents (s1), group-II excitatory interneurons (s2), and Ia-inhibitory interneurons (s3).