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The mysterious origins of microglia

The origin of microglia, the resident macrophage population of the CNS, has been a long-standing matter of debate. Here we discuss two seminal studies published in 2007 in Nature Neuroscience that significantly contributed to a better understanding of microglia ontogeny and homeostasis in the adult brain.

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Fig. 1: Microglia origins and homeostasis in adulthood scenarios.

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Correspondence to Florent Ginhoux.

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Ginhoux, F., Garel, S. The mysterious origins of microglia. Nat Neurosci 21, 897–899 (2018). https://doi.org/10.1038/s41593-018-0176-3

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