Epidemiology and animal research have shown that the offspring of mothers who experience inflammation during pregnancy are at increased risk for psychopathology. A human study links a mother’s inflammation during pregnancy to her newborn’s functional brain organization and the child’s working memory two years later.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Maternal infections during pregnancy and child cognitive outcomes
BMC Pregnancy and Childbirth Open Access 17 November 2022
-
An in vivo brain–bacteria interface: the developing brain as a key regulator of innate immunity
npj Regenerative Medicine Open Access 04 February 2020
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Mennella, J. A., Jagnow, C. P. & Beauchamp, G. K. Pediatrics 107, E88 (2001).
Mehler, J. et al. Cognition 29, 143–178 (1988).
Rudolph, M. D. et al. Nat. Neurosci. https://doi.org/10.1038/s41593-018-0128-y (2018).
Alexander, G. R. & Kotelchuck, M. Public Health Rep. 116, 306–316 (2001).
Guerrini, I., Thomson, A. D. & Gurling, H. D. Neurosci. Biobehav. Rev. 31, 212–220 (2007).
Brown, A. S. Dev. Neurobiol. 72, 1272–1276 (2012).
Estes, M. L. & McAllister, A. K. Science 353, 772–777 (2016).
Smith, S. E. P., Li, J., Garbett, K., Mirnics, K. & Patterson, P. H. J. Neurosci. 27, 10695–10702 (2007).
Graham, A. M. et al. Biol. Psychiatry 83, 109–119 (2018).
Scheller, J., Chalaris, A., Schmidt-Arras, D. & Rose-John, S. Biochim. Biophys. Acta 1813, 878–888 (2011).
Yarkoni, T., Poldrack, R. A., Nichols, T. E., Van Essen, D. C. & Wager, T. D. Nat. Methods 8, 665–670 (2011).
Hughes, C. & Ensor, R. Dev. Psychol 43, 1447–1459 (2007).
Scheinost, D. et al. Pediatr. Res. 81, 214–226 (2017).
Spann, M. N., Monk, C., Scheinost, D. & Peterson, B. S. J. Neurosci. 38, 2877–2876 (2018).
Rosenberg, M. D., Casey, B. J. & Holmes, A. J. Nat. Commun. 9, 589 (2018).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Rosenberg, M.D. Baby brains reflect maternal inflammation. Nat Neurosci 21, 651–653 (2018). https://doi.org/10.1038/s41593-018-0134-0
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41593-018-0134-0
This article is cited by
-
Maternal infections during pregnancy and child cognitive outcomes
BMC Pregnancy and Childbirth (2022)
-
An in vivo brain–bacteria interface: the developing brain as a key regulator of innate immunity
npj Regenerative Medicine (2020)