This plot was generated using LocusZoom1. The -log10(P value) is shown on the left y-axis; position in Mb is on the x-axis. Recombination rates (expressed in centiMorgans cM per Mb; NCBI Build GRCh37; highlighted in blue) are shown on the right y-axis. Pairwise linkage disequilibrium (r2) of each SNP with the top SNP in the region is indicated by its color. Crossed points represent imputed SNPs, circles represent directly genotyped SNPs. The statistical tests used were two-sided; sample size = 23,217.