Supplementary Figure 8: Striatally enriched clusters contain interacting proteins with roles in dopaminergic signalling and drug addiction | Nature Neuroscience

Supplementary Figure 8: Striatally enriched clusters contain interacting proteins with roles in dopaminergic signalling and drug addiction

From: A multiregional proteomic survey of the postnatal human brain

Supplementary Figure 8

. A) Network diagram showing proteins from clusters 26 and 31. These clusters are strongly enriched for protein:protein interactions (adj. p value = 1.55E-15). Coloured edges represent different forms of interaction evidence; experimentally determined (pink), coexpressed (black), curated databases (blue) and text mining (green). The node size represents the extent to which the protein structure has been solved. B) Clusters 26 and 31 are significantly enriched for a number of Biological Process ontology terms. C) KEGG pathway analysis shows significant enrichment for expected pathways, including stimulant addiction and dopaminergic synapse

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