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Analyzing submicron spatial transcriptomics data at their original resolution

FICTURE software addresses a critical challenge in spatial omics analysis: making high-resolution inference with only a few molecules per square micron. This tool fully realizes the potential of contemporary spatial platforms by learning latent spatial factors from the whole transcriptome while preserving the resolution of each technology at scale.

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Fig. 1: Analysis of Seq-Scope-profiled mouse colon using FICTURE.

References

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This is a summary of: Si, Y. et al. FICTURE: scalable segmentation-free analysis of submicron-resolution spatial transcriptomics. Nat. Methods https://doi.org/10.1038/s41592-024-02415-2 (2024).

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Analyzing submicron spatial transcriptomics data at their original resolution. Nat Methods (2024). https://doi.org/10.1038/s41592-024-02416-1

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