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Points of significance

Propensity score matching

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Fig. 1: Causal relationships (arrows) between three covariates (alcohol intake, stress level, caffeine intake) in an observational study that examines the causal effect of smoking on BMD.
Fig. 2: Covariate distributions of all participants in the study and of matched groups.
Fig. 3: Balance between treatment and control groups.
Fig. 4: Bone mineral density reduction between treatment and control groups, allowing for propensity score matching with replacement and weighting.

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Correspondence to Martin Krzywinski.

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C.F.K. is employed by Novartis Pharma.

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Kurz, C.F., Krzywinski, M. & Altman, N. Propensity score matching. Nat Methods 21, 1770–1772 (2024). https://doi.org/10.1038/s41592-024-02405-4

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