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Creating a universal cell segmentation algorithm

Cell segmentation currently involves the use of various bespoke algorithms designed for specific cell types, tissues, staining methods and microscopy technologies. We present a universal algorithm that can segment all kinds of microscopy images and cell types across diverse imaging protocols.

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Fig. 1: Diversity of microscopy images in the challenge dataset for assessing cell segmentation algorithms.


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This is a summary of: Ma, J. et al. The multimodality cell segmentation challenge: toward universal solutions. Nat. Methods (2024).

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Creating a universal cell segmentation algorithm. Nat Methods 21, 950–951 (2024).

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