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Photon-based communication between two neurons in Caenorhabditis elegans

Cells exchange information with one another using secreted chemicals as data carriers. We developed an all-optogenetic synaptic transmission system that replaced a chemical neurotransmitter with emitted photons. This system enabled synthetic signaling between unconnected neurons and the generation of prosthetic synaptic circuits.

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Fig. 1: Rewiring a neuronal circuit using PhAST.


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This is a summary of: Porta-de-la-Riva, M. et al. Neural engineering with photons as synaptic transmitters. Nat. Methods (2023).

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Photon-based communication between two neurons in Caenorhabditis elegans. Nat Methods 20, 653–654 (2023).

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