During the first two years of postnatal development, the human brain undergoes rapid, pronounced changes in size, shape and content. Using high-resolution MRI, we constructed month-to-month atlases of infants 2 weeks to 2 years old, capturing key spatiotemporal traits of early brain development in terms of cortical geometries and tissue properties.
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References
Dickie, D. A. et al. Whole brain magnetic resonance image atlases: a systematic review of existing atlases and caveats for use in population imaging. Front. Neuroinform. 11, 1 (2017). A review article on MRI brain atlases and their utility.
Oishi, K. et al. Baby brain atlases. Neuroimage 185, 865–880 (2019). A review article on MRI atlases of baby brains.
Howell, B. R. et al. The UNC/UMN Baby Connectome Project (BCP): an overview of the study design and protocol development. Neuroimage 185, 891–905 (2019). A paper reporting the study protocol of the Baby Connectome Project.
Ahmad, S. et al. Surface-constrained volumetric registration for the early developing brain. Med. Image Anal. 58, 101540 (2019). A paper describing the nonlinear surface–volume registration method used in our study.
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This is a summary of: Ahmad, S. et al. Multifaceted atlases of the human brain in its infancy. Nat. Methods https://doi.org/10.1038/s41592-022-01703-z (2023).
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Digital brain atlases reveal postnatal development to 2 years of age in human infants. Nat Methods 20, 38–39 (2023). https://doi.org/10.1038/s41592-022-01704-y
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DOI: https://doi.org/10.1038/s41592-022-01704-y
