Researchers describe Retro-Cascorder, a tool that employs prokaryotic retrons and CRISPR integrases to write transcriptional events into the genome of Escherichia coli.
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Research papers
Bhattarai-Kline, S. et al. Recording gene expression order in DNA by CRISPR addition of retron barcodes. Nature 608, 217–225 (2022).
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Tang, L. Tracking the order of transcriptional events in living cells. Nat Methods 19, 1031 (2022). https://doi.org/10.1038/s41592-022-01610-3
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DOI: https://doi.org/10.1038/s41592-022-01610-3