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PROTEOMICS

The adult mouse proteome

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Evidence for at least one protein product from 80% of all mouse genes is reported in a comprehensive proteomic analysis of 41 adult mouse tissues. Comparison of tissue profiles between mouse and human suggests that the fundamental biology of this important model organism is even more different from our own than we thought.

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Fig. 1: A tissue-specific mouse proteome.

References

  1. Omenn, G. S. et al. J. Proteome Res. 20, 5227–5240 (2021).

    CAS  Article  Google Scholar 

  2. Giansanti, P. et al. Nat. Methods https://doi.org/10.1038/s41592-022-01526-y (2022).

  3. Olexiouk, V., Van Criekinge, W. & Menschaert, G. Nucleic Acids Res. 46, D497–D502 (2018). D1.

    CAS  Article  Google Scholar 

  4. Skinnider, M. A. et al. Cell 184, 4073–4089.e17 (2021).

    CAS  Article  Google Scholar 

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Acknowledgements

The author thanks Nicholas Scott for the original idea for the artwork. The author is supported by funding from Genome Canada (264PRO, BeeCSI), the Natural Sciences and Engineering Research Council, and the Canada Foundation for Innovation.

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Correspondence to Leonard J. Foster.

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The author declares no competing interests.

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Foster, L.J. The adult mouse proteome. Nat Methods 19, 792–793 (2022). https://doi.org/10.1038/s41592-022-01546-8

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  • DOI: https://doi.org/10.1038/s41592-022-01546-8

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