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Polishing high-quality genome assemblies

A repeat-aware pipeline corrects structural assembly errors and polishes assembly sequences in large repeats without overcorrection.

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Fig. 1: The polishing strategy to generate CHM13v1.0 and CHM13v1.1 assemblies.


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The authors are supported by NIH NIGMS grant GM132713.

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Correspondence to Kai Wang.

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Fang, L., Wang, K. Polishing high-quality genome assemblies. Nat Methods 19, 649–650 (2022).

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