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3D reconstruction of spatial expression

A novel approach to probabilistically align adjacent multiple tissue slices from spatially resolved transcriptomics data provides unprecedented depth for the investigation of tissue architecture and paves the way for new developments in 3D spatial analytics.

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Fig. 1: Aligning and integrating spatial transcriptomics data across adjacent slices.


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Correspondence to Jean Y. H. Yang.

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Lin, Y., Yang, J.Y.H. 3D reconstruction of spatial expression. Nat Methods 19, 526–527 (2022).

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