Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

ORGANOIDS

Towards spheroid-omics

The MISpheroID knowledgebase records and organizes experimental parameters from thousands of cancer spheroid experiments, revealing heterogeneity and a lack of transparency in key spheroid research reporting practices.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Recommended minimum information for spheroid culture.

References

  1. Vinci, M. et al. BMC Biol. 10, 29 (2012).

    Article  CAS  Google Scholar 

  2. Kamatar, A., Gunay, G. & Acar, H. Polymers 12, (2020).

  3. Peirsman, A. et al. Nat. Methods https://doi.org/10.1038/s41592-021-01291-4 (2021).

  4. Taylor, C. F. et al. Nat. Biotechnol. 26, 889–896 (2008).

    Article  CAS  Google Scholar 

  5. Zanoni, M. et al. Sci. Rep. 6, 19103 (2016).

    Article  CAS  Google Scholar 

  6. Vande Voorde, J. et al. Sci. Adv. 5, eaau7314 (2019).

    Article  Google Scholar 

  7. Vadivelu, R. K. et al. Micromachines 8, 94 (2017).

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported by grants from the National Institutes of Health (NIH) National Cancer Institute (NCI) (New Innovator Award DP2CA250382-01), the National Science Foundation (NSF) (DMS1763272) and the Simons Foundation (594598 QN).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Timothy L. Downing.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Downing, T.L. Towards spheroid-omics. Nat Methods 18, 1283–1285 (2021). https://doi.org/10.1038/s41592-021-01311-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41592-021-01311-3

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer