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Nanopore-detectable reporter proteins

Nature Methods volume 18, page 1149 (2021)Cite this article

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NanoporeTERs, engineered reporter proteins, can be detected on MinION nanopore sensor arrays.

Traditional reporter proteins such as fluorescent proteins and their variants have been very popular for tracking genetic regulation in biological systems. However, the number of unique reporters that can be used simultaneously is still small, and yet investigating many targets is often desirable for more comprehensive and efficient analysis of biological systems. Jeff Nivala, with other researchers at the University of Washington in Seattle, has developed a new class of reporter proteins, nanopore-addressable protein tags engineered as reporters (NanoporeTERs (NTERs)), that allow greater multiplexing.

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  1. Nature Methods http://www.nature.com/nmeth

    Arunima Singh

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  1. Arunima Singh
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Correspondence to Arunima Singh.

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Singh, A. Nanopore-detectable reporter proteins. Nat Methods 18, 1149 (2021). https://doi.org/10.1038/s41592-021-01297-y

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  • DOI: https://doi.org/10.1038/s41592-021-01297-y

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