Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

MICROSCOPY

Weighing single protein complexes on the go

Dynamic mass photometry, a method based on optical imaging of unlabeled proteins, enables direct observation and tracking of single-protein interactions on lipid membranes.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1

References

  1. Foley, E. D. B, Kushwah, M. S., Young, G. & Kukura, P. Nat. Methods https://doi.org/10.1038/s41592-021-01261-w (2021).

  2. Heermann, T., Steiert, F., Ramm, B., Hundt, N. & Schwille, P. Nat. Methods https://doi.org/10.1038/s41592-021-01260-x (2021).

  3. Lelek, M. et al. Nat. Rev. Methods Primers 1, 39 (2021).

    Article  Google Scholar 

  4. Stehr, F. et al. Nat. Commun. 12, 4432 (2021).

    Article  CAS  Google Scholar 

  5. Ortega Arroyo, J. et al. Nano Lett. 14, 2065–2070 (2014).

    Article  CAS  Google Scholar 

  6. Piliarik, M. & Sandoghdar, V. Nat. Commun. 5, 4495 (2014).

    Article  CAS  Google Scholar 

  7. Young, G. et al. Science 360, 423–427 (2018).

    Article  CAS  Google Scholar 

  8. Loose, M., Fischer-Friedrich, E., Ries, J., Kruse, K. & Schwille, P. Science 320, 789–792 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marek Piliarik.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Vala, M., Piliarik, M. Weighing single protein complexes on the go. Nat Methods 18, 1159–1160 (2021). https://doi.org/10.1038/s41592-021-01263-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41592-021-01263-8

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing