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Triangulating spatial relationships from single-cell interaction maps

A combined experimental and computational approach to transcriptomic profiling of cell ‘multiplets’ enables the reconstruction of cell–cell interactions and higher-order structural features of biological tissues.

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Fig. 1: Reconstruction of tissue architectures using CIM-seq.


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Correspondence to Daniel E. Wagner.

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Wagner, D.E. Triangulating spatial relationships from single-cell interaction maps. Nat Methods 18, 867–869 (2021).

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