Researchers work towards improving the efficiency and specificity of prime editors, as well as their delivery system in plants and animals.
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Research papers
Lin, Q. et al. High-efficiency prime editing with optimized, paired pegRNAs in plants. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-00868-w (2021).
Jin, S. et al. Genome-wide specificity of prime editors in plants. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-00891-x (2021).
Petri, K. et al. CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-00901-y (2021).
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Tang, L. Prime editing progress. Nat Methods 18, 592 (2021). https://doi.org/10.1038/s41592-021-01188-2
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DOI: https://doi.org/10.1038/s41592-021-01188-2
