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GENE EXPRESSION

Studying divergence in human–chimp hybrid cells

Fusions of human and chimp iPS cells help study how divergence in gene expression affects phenotypic traits.

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Research papers

  • Agoglia, R. M. et al. Primate cell fusion disentangles gene regulatory divergence in neurodevelopment. Nature 592, 421–427 (2021).

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  • Gokhman, D. et al. Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution. Nat. Genet. 53, 467–476 (2021).

    Article  CAS  Google Scholar 

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Correspondence to Nina Vogt.

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Vogt, N. Studying divergence in human–chimp hybrid cells. Nat Methods 18, 444 (2021). https://doi.org/10.1038/s41592-021-01157-9

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  • DOI: https://doi.org/10.1038/s41592-021-01157-9

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