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3D GENOMICS

Benchmarking experiments with polymer modeling

Nature Methods volume 18, pages 456–457 (2021)Cite this article

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A study applies polymer physics to assess the advantages and limitations of three sequencing-based approaches for determining the structure of genomes and genomic domains.

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Fig. 1: Computational modeling bypasses the difficulties for benchmarking and assessing the performances of Hi-C, SPRITE and GAM for determining the structure of genomes and genomic domains.

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Authors and Affiliations

  1. CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

    Marc A. Marti-Renom

  2. Centre for Genomic Regulation (CRG, Barcelona Institute of Science and Technology BIST, Barcelona, Spain

    Marc A. Marti-Renom

  3. Universitat Pompeu Fabra (UPF), Barcelona, Spain

    Marc A. Marti-Renom

  4. ICREA, Barcelona, Spain

    Marc A. Marti-Renom

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  1. Marc A. Marti-Renom
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Correspondence to Marc A. Marti-Renom.

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Marti-Renom, M.A. Benchmarking experiments with polymer modeling. Nat Methods 18, 456–457 (2021). https://doi.org/10.1038/s41592-021-01134-2

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