Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

COMPUTATIONAL STRUCTURAL BIOLOGY

Martini 3: a coarse-grained force field with an eye for atomic detail

Souza et al. present the latest release of the popular and widely used force field for near-atomistic coarse-grained biomolecular simulations.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Fig. 1: Perspectives in near-atomistic coarse-graining.

References

  1. 1.

    Risselada, H. J. & Marrink, S. J. Proc. Natl Acad. Sci. USA 105, 17367–17372 (2008).

    CAS  Article  Google Scholar 

  2. 2.

    van den Bogaart, G. et al. Nature 479, 552–555 (2011).

    Article  Google Scholar 

  3. 3.

    D’Agostino, M., Risselada, H. J., Lürick, A., Ungermann, C. & Mayer, A. Nature 551, 634–638 (2017).

    Article  Google Scholar 

  4. 4.

    Ingólfsson, H. I. et al. J. Am. Chem. Soc. 136, 14554–14559 (2014).

    Article  Google Scholar 

  5. 5.

    Pezeshkian, W., König, M., Wassenaar, T. A. & Marrink, S. J. Nat. Commun. 11, 2296 (2020).

    CAS  Article  Google Scholar 

  6. 6.

    Souza, P. C. et al. Nat. Commun. 11, 3714 (2020).

    CAS  Article  Google Scholar 

  7. 7.

    Poma, A. B., Cieplak, M. & Theodorakis, P. E. J. Chem. Theory Comput. 13, 1366–1374 (2017).

    CAS  Article  Google Scholar 

  8. 8.

    Seo, S. & Shinoda, W. J. Chem. Theory Comput. 15, 762–774 (2019).

    CAS  Article  Google Scholar 

  9. 9.

    Bassereau, P. et al. J. Phys. D Appl. Phys. 51, 343001, https://doi.org/10.1088/1361-6463/aacb98 (2018).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

The author thanks K. Stroh, L. Endter, A. Soleimani, J. Methorst, N. van Hilten and A. Sevink for fruitful discussions. The Dutch NWO is acknowledged for funding (Vidi grant, no. 723.016.005).

Author information

Affiliations

Authors

Corresponding author

Correspondence to H. Jelger Risselada.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Risselada, H.J. Martini 3: a coarse-grained force field with an eye for atomic detail. Nat Methods 18, 342–343 (2021). https://doi.org/10.1038/s41592-021-01111-9

Download citation

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing