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STEM CELL BIOLOGY

Assembling organs in vitro

Assembloids recapitulate organ spatial organization and interaction with high fidelity.

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Research papers

  • Kim, E. et al. Creation of bladder assembloids mimicking tissue regeneration and cancer. Nature 588, 664–669 (2020).

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  • Miura, Y. et al. Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells. Nat. Biotechnol. 38, 1421–1430 (2020).

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  • Andersen, J. et al. Generation of functional human 3D cortico-motor assembloids. Cell 183, 1913–1929 (2020).

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Correspondence to Madhura Mukhopadhyay.

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Mukhopadhyay, M. Assembling organs in vitro. Nat Methods 18, 119 (2021). https://doi.org/10.1038/s41592-021-01068-9

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