BIOPHYSICS

A new way to see RNAs

Producing reliable atomic- or close-to-atomic-resolution structures of RNA-only molecules has been a formidable task. Ribosolve can solve sub-nanometer-resolution cryo-EM structures of unbound RNA molecules with unprecedented accuracy and speed.

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Fig. 1: The hc16 ligase product structure determined with the Ribosolve pipeline.

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Correspondence to Jane S. Richardson.

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Richardson, J.S. A new way to see RNAs. Nat Methods 17, 663–664 (2020). https://doi.org/10.1038/s41592-020-0888-7

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