Dietary guidelines advise substituting saturated fats with unsaturated fats. We used detailed blood fat composition profiling in diet trials and population studies to confirm that a moderate high-fat diet from plant oils is better for metabolism and heart health than a diet with similar fat levels from animal sources.
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References
World Health Organization. Saturated Fatty Acid and Trans-Fatty Acid Intake for Adults and Children: WHO Guideline (World Health Organization, 2023). The updated WHO guidelines provide a comprehensive synthesis and evaluation of evidence for effects of reduced saturated fat intake on cardiovascular disease risk.
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This is a summary of: Eichelmann, F. et al. Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition. Nat. Med. https://doi.org/10.1038/s41591-024-03124-1 (2024).
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Blood lipid profiling indicates that dietary fat quality is associated with cardiometabolic risk. Nat Med (2024). https://doi.org/10.1038/s41591-024-03234-w
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DOI: https://doi.org/10.1038/s41591-024-03234-w
