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Testing pooled samples enables universal screening of congenital cytomegalovirus infection

The implementation of PCR tests of pooled saliva samples for universal screening of congenital cytomegalovirus infection was assessed in 15,805 neonates over 13 months. This extensive analysis revealed the high feasibility and empirical efficiency of the pooled testing approach, which had a clinically insignificant loss of sensitivity.

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Fig. 1: Newborn cCMV screening scheme and performance rates.


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This is a summary of: Merav, L. et al. Implementation of pooled saliva tests for universal screening of cCMV infection. Nat. Med. (2024).

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Testing pooled samples enables universal screening of congenital cytomegalovirus infection. Nat Med 30, 952–953 (2024).

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