Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Neurological disease

Facilitating limb movement after stroke

Epidural spinal cord stimulation improved upper limb function in two participants after stroke, revealing a potentially exciting new tool for stroke recovery.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Effect of SCS on upper limb movement after stroke.

References

  1. Ghassemi, M. & Kamper, D. G. In Neurorehabilitation Technology (eds. Reinkensmeyer, D. J. et al.) 114–134 (Springer, 2022).

  2. Powell, M. P. et al. Nat. Med. https://doi.org/10.1038/s41591-022-02202-6 (2023).

    Article  PubMed  Google Scholar 

  3. Seanez, I., Capogrosso, M., Minassian, K. & Wagner, F. In Neurorehabilitation Technology (eds. Reinkensmeyer, D. J. et al.) 369–400 (Springer, 2022).

  4. Hachmann, J. T. et al. J. Neurophysiol. 126, 1843–1859 (2021).

    Article  PubMed  Google Scholar 

  5. Lu, D. C. et al. Neurorehabil. Neural Repair 30, 951–962 (2016).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Lin, D. J. et al. Stroke 50, 3569–3577 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Mehrholz, J., Pohl, M., Platz, T., Kugler, J. & Elsner, B. Cochrane Database Syst. Rev https://doi.org/10.1002/14651858.CD006876.pub5 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Stinear, C. M., Lang, C. E., Zeiler, S. & Byblow, W. D. Lancet Neurol 19, 348–360 (2020).

    Article  CAS  PubMed  Google Scholar 

  9. Ward, N. S., Brander, F. & Kelly, K. J. Neurol. Neurosurg. Psychiatry 90, 498–506 (2019).

    Article  PubMed  Google Scholar 

  10. Schwerz de Lucena, D., Rowe, J., Chan, V. & Reinkensmeyer, D. J. Sensors 21, 1502 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  11. Popovic, M. R., Masani, K. & Milosevic, M. In Neurorehabilitation Technology (eds. Reinkensmeyer, D. J. et al.) 401–428 (Springer, 2022).

  12. Norman, S. L., Wolpaw, J. R. & Reinkensmeyer, D. J. Brain Commun. 4, fcac264 (2022).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to David J. Reinkensmeyer.

Ethics declarations

Competing interests

D.J.R. has a financial interest in Hocoma A.G. and Flint Rehabilitation Devices LLC, companies that develop and sell rehabilitation devices. The terms of these arrangements have been reviewed and approved by the University of California, Irvine, in accordance with its conflict of interest policies.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Reinkensmeyer, D.J., Farrens, A.J. & Kamper, D.G. Facilitating limb movement after stroke. Nat Med 29, 535–536 (2023). https://doi.org/10.1038/s41591-023-02233-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41591-023-02233-7

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research