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Genomic autopsy offers answers for pregnancy loss and perinatal death

The cause of pregnancy loss or perinatal death often remains unexplained, even following a standard autopsy. Comprehensive genomic investigation of pregnancy loss or perinatal death identifies a cause in over 50% of cases, particularly where congenital abnormalities are present. Causes of stillbirths without congenital abnormalities remain difficult to identify.

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Fig. 1: Diagnostic yield of genomic autopsy.


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This is a summary of: Byrne, A. B. et al. Genomic autopsy to identify underlying causes of pregnancy loss and perinatal death. Nat. Med. (2023).

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Genomic autopsy offers answers for pregnancy loss and perinatal death. Nat Med 29, 41–42 (2023).

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