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Gut microbiota

Understanding and predicting the efficacy of FMT

Clinical evaluation of FMT is progressing without an adequate understanding of the underlying ecological dynamics; studies are now beginning to fill these gaps, but consensus will be needed on many fronts.

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Fig. 1: Factors associated with ecological dynamics after FMT, and with FMT success.

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Correspondence to Harry Sokol.

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H.S. reports lecture fee, board membership or consultancy from Carenity, AbbVie, Astellas, Amgen Servier, Danone, Ferring, Mayoly Spindler, MSD, Novartis, Roche, Tillots, BiomX, Biose, Novartis,Takeda, Fresenius, Adaren Nestle, Sanofi and Biocodex, possessed stocks from Enterome and is co-founder of Exeliom Biosciences.

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Lavelle, A., Sokol, H. Understanding and predicting the efficacy of FMT. Nat Med 28, 1759–1760 (2022). https://doi.org/10.1038/s41591-022-01991-0

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