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A life-course approach to cardiovascular disease prevention

Preventing atherosclerotic cardiovascular disease in adults will require innovative public health approaches focused on children and families, to improve risk factor trajectories across the lifespan and prioritize children at highest risk of future disease.

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Fig. 1: Atherosclerosis progression from childhood to adulthood.


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Correspondence to James A. de Lemos.

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Competing interests

J.A.d.L. has received personal fees for participating in steering or data safety monitoring committees from Amgen, Regeneron, Verve Therapeutics, Novo Nordisc, Eli Lilly and Astra Zeneca. A.M.N. has received funding for research to her institution from BMS, Esperion, Amgen, and Janssen, and personal fees from Amarin, Amgen, Astra Zeneca, BI, Bayer, CSL, Esperion, Janssen, Lilly, Sanofi, Regeneron, NovoNordisk, Novartis, New Amsterdam, and Pfizer.

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de Lemos, J.A., Navar, A.M. A life-course approach to cardiovascular disease prevention. Nat Med 28, 1133–1134 (2022).

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