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The unique challenges of studying the genetics of diet and nutrition

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Fig. 1: Main methodological considerations of MR studies when implemented for nutritional exposures.

References

  1. Lawlor, D. A. et al. Stat. Med. 27, 1133 (2008).

    Article  Google Scholar 

  2. Hernán, M. A. & Robins, J. M. Causal Inference: What If? (CRC Press, 2021).

  3. Merino, J. et al. Nat. Hum. Behav. (in the press).

  4. Ibsen, D. et al. Am. J. Clin. Nutr. 113, 294 (2021).

    Article  Google Scholar 

  5. Millwood, I. Y. et al. Lancet 393, 1831 (2019).

    Article  Google Scholar 

  6. National Survey of Drug Use and Health (NSDUH) Releases (SAMHSA, 2019); https://www.samhsa.gov/data/release/2019-national-survey-drug-use-and-health-nsduh-releases

  7. Rosoff, D. B. et al. PLoS Med. 17, e1003410 (2020).

    Article  Google Scholar 

Download references

Acknowledgements

We thank S. Swanson (Erasmus University Rotterdam) and J. Speakman (University of Aberdeen) for their thoughtful contributions to earlier versions of the manuscript. Funding was received from National Institutes of Health grant P30DK40561 (J.M.) and American Diabetes Association grant no. 7-21-JDFM-005 (J.M.).

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J.M. and D.K.T. contributed to the original draft and editing of the manuscript.

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Correspondence to Deirdre K. Tobias.

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The authors declare no competing interests.

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Merino, J., Tobias, D.K. The unique challenges of studying the genetics of diet and nutrition. Nat Med 28, 221–222 (2022). https://doi.org/10.1038/s41591-021-01626-w

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