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Engineered yeast tune down gut inflammation

A yeast strain engineered to regulate levels of pathogenic metabolites in the gut provides protection against colitis in mouse models.

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Fig. 1: Yeast engineered to regulate eATP levels in the inflamed gut.


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Correspondence to Cathryn R. Nagler.

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Competing interests

C.R.N. is the president and co-founder of ClostraBio.

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Mimee, M., Nagler, C.R. Engineered yeast tune down gut inflammation. Nat Med 27, 1150–1151 (2021).

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