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BIOENGINEERING

Engineered yeast tune down gut inflammation

A yeast strain engineered to regulate levels of pathogenic metabolites in the gut provides protection against colitis in mouse models.

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Fig. 1: Yeast engineered to regulate eATP levels in the inflamed gut.

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Correspondence to Cathryn R. Nagler.

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C.R.N. is the president and co-founder of ClostraBio.

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Mimee, M., Nagler, C.R. Engineered yeast tune down gut inflammation. Nat Med 27, 1150–1151 (2021). https://doi.org/10.1038/s41591-021-01420-8

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