Interleukin-6 levels when separated by IL6R Asp358Ala polymorphism status showed no statistical difference across a. CH mutation status and b. HIV status. The centre line of the box depicts the mean IL-6 value with the lower and upper bounds of the boxes representing the 25th and 75th percentile values, respectively. The lower bound of the whisker indicates the minimum, defined as the 25th percentile minus 1.5x the interquartile range, and the upper bound of the whisker indicates the maximum, defined as the 75th percentile plus 1.5x the interquartile range. Overall p-values (figure inset) were generated using the Kruskal-Wallis test. Tests for significant differences in the median across groups were done by generating p-values using post-hoc pairwise two-sided multiple comparison analysis (Dwass, Steel, Critchlow-Fligner Method). Outliers have been removed for box plot presentation only; p-values were calculated including outliers. Outliers were defined as values greater than 1.5 times the IQR above the third quartile.