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Reply to: Concerns over calculating injury-related deaths associated with temperature

The Original Article was published on 16 November 2020

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Data availability

ERA5 temperature data are downloadable from Vital statistics files with geographical information can be requested through submission of a proposal to the NCHS (

Code availability

The computer code for the Bayesian model used in Parks et al.2 is available at


  1. Semenza, J. C. et al. Heat-related deaths during the July 1995 heat wave in Chicago. N. Engl. J. Med. 335, 84–90 (1996).

    CAS  Article  Google Scholar 

  2. Parks, R. M. et al. Anomalously warm temperatures are associated with increased injury deaths. Nat. Med. 26, 65–70 (2020).

    CAS  Article  Google Scholar 

  3. Burke, M. et al. Higher temperatures increase suicide rates in the United States and Mexico. Nat. Clim. Change 8, 723–729 (2018).

    Article  Google Scholar 

  4. Pope, C. A., Ezzati, M. & Dockery, D. W. Fine-particulate air pollution and life expectancy in the United States. N. Engl. J. Med. 360, 376–386 (2009).

    CAS  Article  Google Scholar 

  5. Bennett, J. E. et al. National and county life expectancy loss from particulate matter pollution in the USA. PLoS Med. 16, e1002856 (2019).

    Article  Google Scholar 

  6. Kuulasmaa, K. et al. Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet 355, 675–687 (2000).

    CAS  Article  Google Scholar 

  7. Mitchell, D. et al. Concerns over calculating injury-related deaths associated with temperature. Nat. Med. (2020).

  8. Baldwin, J. W., Dessy, J. B., Vecchi, G. A. & Oppenheimer, M. Temporally compound heat wave events and globÿal warming: an emerging hazard. Earth's Future 7, 411–427 (2019).

    Article  Google Scholar 

  9. Robertson, L. Climate Change, weather and road deaths. Inj. Prev. 24, 232–235 (2018).

    Article  Google Scholar 

  10. Cohen, A. J. et al. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet 389, 1907–1918 (2017).

    Article  Google Scholar 

  11. Murray, C. J. L., Ezzati, M., Lopez, A. D., Rodgers, A. & Vander Hoorn, S. Comparative quantification of health risks: conceptual framework and methodological issues. Popul. Health Metr. 1, 1 (2003).

    Article  Google Scholar 

  12. Bailis, R., Ezzati, M. & Kammen, D. M. Mortality and greenhouse gas impacts of biomass and petroleum energy futures in Africa. Science 308, 98–103 (2005).

    CAS  Article  Google Scholar 

  13. Foreman, K. J., Li, G., Best, N. & Ezzati, M. Small area forecasts of cause-specific mortality: application of a Bayesian hierarchical model to US vital registration data. J. R. Stat. Soc. C 66, 121–139 (2017).

    Article  Google Scholar 

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Authors and Affiliations



R.M.P. and M.E. wrote the first draft of the paper. J.E.B., H.T.-W., V.K., R.T. and G.D. contributed to finalizing the paper.

Corresponding author

Correspondence to Majid Ezzati.

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Competing interests

M.E. reports a charitable grant from AstraZeneca Young Health Programme and personal fees from Prudential, all outside the submitted work; all other authors declare no competing interests.

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Parks, R.M., Bennett, J.E., Tamura-Wicks, H. et al. Reply to: Concerns over calculating injury-related deaths associated with temperature. Nat Med 26, 1827–1828 (2020).

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