Combining liquid biopsies and PET-CT for early cancer detection

A simple blood test performed alongside PET-CT imaging facilitates early cancer detection in asymptomatic women.

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Fig. 1: A liquid-biopsy test was assessed in a cohort of women with no history of cancer in the DETECT-A study.


  1. 1.

    van der Pol, Y. & Mouliere, F. Cancer Cell 36, 350–368 (2019).

    Article  Google Scholar 

  2. 2.

    Lennon, A. M. et al. Science (2020).

    Article  PubMed  Google Scholar 

  3. 3.

    Chabon, J. J. et al. Nature 580, 245–251 (2020).

    CAS  Article  Google Scholar 

  4. 4.

    Cristiano, S. et al. Nature 570, 385–389 (2019).

    CAS  Article  Google Scholar 

  5. 5.

    Shen, S. Y. et al. Nature 563, 579–583 (2018).

    CAS  Article  Google Scholar 

  6. 6.

    Liu, M. C. et al. Ann. Oncol. 31, 745–759 (2020).

    Article  Google Scholar 

  7. 7.

    Dawson, S. J. et al. N. Engl. J. Med. 368, 1199–1209 (2013).

    CAS  Article  Google Scholar 

  8. 8.

    Cohen, J. D. et al. Science 359, 926–930 (2018).

    CAS  Article  Google Scholar 

  9. 9.

    Wong, S. Q., Tothill, R. W., Dawson, S. J. & Hicks, R. J. J. Nucl. Med. 58, 869–870 (2017).

    Article  Google Scholar 

  10. 10.

    Srivastava, S. et al. Nat. Rev. Cancer 19, 349–358 (2019).

    CAS  Article  Google Scholar 

  11. 11.

    Hu, Z., Li, Z., Ma, Z. & Curtis, C. Nat. Genet. (2020).

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Sarah-Jane Dawson.

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Wong, S.Q., Dawson, S. Combining liquid biopsies and PET-CT for early cancer detection. Nat Med (2020).

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