Mapping postprandial responses sets the scene for targeted dietary advice

A machine-learning model can predict differences between people in how they respond to meals.

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Fig. 1: The PREDICT 1 study used a machine-learning model to predict a person’s unique postprandial response to meals of varying composition.


  1. 1.

    Berry, S. et al. Nat. Med. (2020).

  2. 2.

    Temelkova-Kurktschiev, T. S. et al. Diabetes Care 23, 1830–1834 (2000).

    CAS  Article  Google Scholar 

  3. 3.

    Nordestgaard, B. G. & Varbo, A. Lancet 384, 626–635 (2014).

    CAS  Article  Google Scholar 

  4. 4.

    Zeevi, D. et al. Cell 163, 1079–1094 (2015).

    CAS  Article  Google Scholar 

  5. 5.

    Bao, J., Atkinson, F., Petocz, P., Willett, W. C. & Brand-Miller, J. C. Am. J. Clin. Nutr. 93, 984–996 (2011).

    CAS  Article  Google Scholar 

  6. 6.

    Buyken, A. E., Mitchell, P., Ceriello, A. & Brand-Miller, J. Diabetologia 53, 406–418 (2010).

    CAS  Article  Google Scholar 

  7. 7.

    Wycherley, T. P., Moran, L. J., Clifton, P. M., Noakes, M. & Brinkworth, G. D. Am. J. Clin. Nutr. 96, 1281–1298 (2012).

    CAS  Article  Google Scholar 

  8. 8.

    Zafar, M. I. et al. Am. J. Clin. Nutr. 110, 891–902 (2019).

    Article  Google Scholar 

  9. 9.

    Livesey, G. et al. Nutrients 11, 1280 (2019).

    CAS  Article  Google Scholar 

  10. 10.

    Livesey, G. & Livesey, H. Quality & Outcomes 3, 52–69 (2019).

    Google Scholar 

  11. 11.

    Celis-Morales, C. et al. Int. J. Epidemiol. 46, 578–588 (2017).

    PubMed  Google Scholar 

  12. 12.

    Ordovas, J. M., Ferguson, L. R., Tai, E. S. & Mathers, J. C. Br. Med. J. 361, bmj.k2173 (2018).

    Article  Google Scholar 

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Correspondence to Jennie Brand-Miller or Anette Buyken.

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Competing interests

J.B.-M. is the co-author of books about nutrition and the glycemic index of foods; is the president of the Glycemic Index Foundation, a not-for-profit food endorsement program; and oversees a glycemic index testing service at the University of Sydney. J.B.-M. and A.B. are a members of the International Carbohydrate Quality Consortium, and A.B. is a member of the Carbohydrate Task Force, ILSI Europe.

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Brand-Miller, J., Buyken, A. Mapping postprandial responses sets the scene for targeted dietary advice. Nat Med 26, 828–830 (2020).

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