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CANCER THERAPY

Local cellular cues that influence the immunology of colorectal cancer treatment

Therapeutic interventions in colorectal cancer are dependent on immune responses to dying epithelial cells that are modulated by specific members of the gut microbiota.

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Fig. 1: A link among apoptosis, the microbiome and immune responses in the treatment of colorectal cancer.

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Correspondence to Gregory P. Donaldson or Daniel Mucida.

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Donaldson, G.P., Mucida, D. Local cellular cues that influence the immunology of colorectal cancer treatment. Nat Med 26, 824–826 (2020). https://doi.org/10.1038/s41591-020-0902-8

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