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PUBLIC HEALTH

Salt substitution to lower population blood pressure

Nature Medicine volume 26, pages 313–314 (2020)Cite this article

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A study in Peru of community-wide implementation of the use of salt substitution strengthens the evidence for its use as a public-health strategy to reduce blood pressure and, thus, chronic disease risk.

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Fig. 1: Potential impact of replacing the usual salt with a potassium-enriched salt substitute on sodium and potassium intake, and the associated health outcomes.

References

  1. He, F. J. & MacGregor, G. A. Nat. Rev. Cardiol. 15, 371–377 (2018).

    Article  Google Scholar 

  2. He, F. J. & MacGregor, G. A. Br. Med. J. 323, 497–501 (2001).

    Article  CAS  Google Scholar 

  3. Newberry, S.J. et al. Comparative Effectiveness Review No. 206 (Agency for Healthcare Research and Quality, 2018); https://doi.org/10.23970/AHRQEPCCER206

  4. Bernabe-Ortiz, A. et al. Nat. Med. https://doi.org/10.1038/s41591-020-0754-2 (2020).

    Article  PubMed  Google Scholar 

  5. He, F. J., Li, J. & Macgregor, G. A. Br. Med. J. 346, f1325 (2013).

    Article  Google Scholar 

  6. He, F. J. & MacGregor, G. A. Prog. Cardiovasc. Dis. 52, 363–382 (2010).

    Article  CAS  Google Scholar 

  7. Chang, H. Y. et al. Am. J. Clin. Nutr. 83, 1289–1296 (2006).

    Article  CAS  Google Scholar 

  8. Huang, L. et al. Am. Heart. J. 221, 136–145 (2020).

    Article  CAS  Google Scholar 

  9. Karppanen, H. & Mervaala, E. Prog. Cardiovasc. Dis. 49, 59–75 (2006).

    Article  CAS  Google Scholar 

  10. Trieu, K. et al. PLoS One 10, e0130247 (2015).

    Article  Google Scholar 

  11. Scientific Advisory Committee on Nutrition and the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/660526/SACN_COT_-_Potassium-based_sodium_replacers.pdf (2017).

  12. Sacks, F. M. et al. N. Engl. J. Med. 344, 3–10 (2001).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK

    Feng J. He, Monique Tan, Jing Song & Graham A. MacGregor

Authors
  1. Feng J. He
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  2. Monique Tan
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  3. Jing Song
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  4. Graham A. MacGregor
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Correspondence to Feng J. He.

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Competing interests

F.J.H. is a member of Consensus Action on Salt and Health (CASH) and World Action on Salt and Health (WASH); both are non-profit charitable organizations, and F.J.H. does not receive any financial support from either. G.A.M. is Chairman of Blood Pressure UK (BPUK), Chairman of CASH and Chairman of WASH; all are non-profit charitable organizations, and G.A.M. does not receive any financial support from any of them.

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He, F.J., Tan, M., Song, J. et al. Salt substitution to lower population blood pressure. Nat Med 26, 313–314 (2020). https://doi.org/10.1038/s41591-020-0784-9

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